Reference intervals for plasma free metanephrines with an age adjustment for …

Background: Measurements of plasma normetanephrine and metanephrine provide a useful diagnostic test for phaeochromocytoma,but this depends on appropriate reference intervals. Upper cut-offs set too high compromise diagnostic sensitivity,whereas set too low, false-positives are a problem. This study aimed to establish optimal reference intervals forplasma normetanephrine and metanephrine. Metho…