Inhibition of influenza virus replication by constrained peptides targeting n…

Background: Because of high mutation rates, new drugresistant viruses are rapidly evolving, thus making the necessary control of influenza virus infection difficult.Methods: We screened a constrained cysteine-rich peptide library mimicking m-conotoxins from Conus geographus and a proline-rich peptide library mimicking lebocin 1 and 2 from Bombyx mori by using influenza virus RNA polymerase (…