Animal models for percutaneous absorption

Animalmodels are important tools to predict human in vivo percutaneous absorption/penetration. Monkey, pig, rat, rabbit,guinea pig, hairless rodents, such as hairless rat, hairless mouse, hairless guinea pig and hairless dog, are among the most used animals for this purpose. Each animal model has its own advantages and weakness or limitation. To better correlate animal data with human skin abso…