Abstract. A new approach to micellar polymerization is described. It is well known that hydrocarbons and fluorocarbons exhibit local phase segregation (demixing) owing to mutual antipathy; here this effect is employed in monomer swollen micelles with appropriate combinations of hydrocarbon and fluorocarbon monomers and surfactants. A matrix of these hydro- and fluorocarbon components has be…
Abstract. To improve the dissolution rate of ibuprofen, a model poorly water soluble drug, self-nanoemulsifying drug delivery systems (SNEDDS) were developed. Various surfactants and oils were screened as candidates for SNEDDS on the basis of droplet size of the resulting emulsions. The influence of the constituent structure, concentration and the composition of SNEDDS formulations, and the…