The Effects of Amlodipine and S(-)-Amlodipine on Vascular Endothelial Functio…

Background Amlodipine has been shown to improve vascular endothelial function in hypertensive patients, but whether S(-)-amlodipine has a similar effect remains controversial. This study compared the effects of amlodipine and S(-)-amlodipine on vascular endothelial function in hypertensive patients and investigated relevant mechanisms of action in cell culture. Methods Twenty-four patient…