Removal of Botulinum Neurotoxin A Surrogate from Reusable Medical Device Surf…

Abstract: Botulinum neurotoxin A (BoNT/A) is on the national select agent registry and can be an extremely potent biotoxin if weaponized. It blocks neuromuscular transmission by decreasing acetylcholine release. This may be a serious problem if expensive reusable medical devices such as ventilators or anesthesia machines are accidentally or deliberately contaminated. Since transfer of BoNT/A f…