Ditapis dengan
Specific targeting and killing of Gram-negative pathogens with an engineered …
Mode of action of pesticin and an engineered hybrid protein: (1) The Pesticin molecule consists of a N-terminal “FyuA binding” and a C-terminal lysozyme-like domain. After traversing the outer membrane pesticin degrades the peptidoglycan structural layer present in the periplasm resulting in cell killing. This translocation depends on an outer membrane protein and virulence factor—FyuA—…
- Edisi
- 4:1; January 1, 2013
- ISBN/ISSN
- doi.org/10.1073/pnas
- Deskripsi Fisik
- Virulence 4:1, 90–96; January 1, 2013
- Judul Seri
- Virulence
- No. Panggil
- -
Structural engineering of a phage lysin that targets Gram-negative pathogens
Bacterial pathogens are becoming increasingly resistant to antibiotics. As an alternative therapeutic strategy, phage therapy reagents containing purified viral lysins have been developed against Grampositive organisms but not against Gram-negative organisms due to the inability of these types of drugs to cross the bacterial outer membrane. We solved the crystal structures of a Yersinia pestis …
- Edisi
- June 19, 2012 ∣ vol. 109 ∣ no. 25
- ISBN/ISSN
- doi/10.1073/pnas.120
- Deskripsi Fisik
- PNAS ∣ June 19, 2012 ∣ vol. 109 ∣ no. 25 ∣ 9857–9862
- Judul Seri
- PNAS
- No. Panggil
- -
Karya Umum 
Filsafat 
Agama 
Ilmu-ilmu Sosial 
Bahasa 
Ilmu-ilmu Murni 
Ilmu-ilmu Terapan 
Kesenian, Hiburan, dan Olahraga 
Kesusastraan 
Geografi dan Sejarah