Facilitating the indirect detection of genomic DNA in an electrochemical DNA …

a b s t r a c t A common problem in applying biosensors for the detection of genomic DNA is detecting short sequences in large amounts of long double stranded DNA. A gold electrode modified with a conductive nanocomposite, poly(3,4-ethylene-dioxythiophene), and gold nanoparticles was functionalized with 2,6- Pyridinedicarboxylic acid. Immobilization of a 20-mer DNA probe as the bioreceptor wa…