Identification of a rare variant haemoglobin (Hb Sinai-Baltimore)causing spur…

Commonly used methods for assay of haemoglobin A1c (HbA1c) are susceptible to interference from the presence of haemoglobin variants. In many systems, the common variants can be identified but scientists and pathologists must remain vigilant for more subtle variants that may result in spuriously high or low HbA1c values. It is clearly important to recognize these events whether HbA1c is being u…