Characterization of Recombinant Vaccinia Viruses by MLPA Technology

Abstract: Recombinant vaccinia viruses are popular tools for the delivery of heterologous genes for vaccination purposes. Vaccinia viruses are generally classified as risk group 2 biological agents (in accordance to directive 2000/54/EC), with the attenuated strain Modified vaccinia virus Ankara (MVA) being classified into risk group 1. For the analytical surveillance of genetic engineering op…