Near-infrared (NIR) persistent phosphor ZnGa 2 O 4 :Cr 3+ (ZGC) has unique deep-tissue rechargeable afterglow properties. However, the current synthesis leads to agglomerated products with irregular morphologies and wide size distributions. Herein, we report on in vivo rechargeable mesoporous SiO 2 /ZnGa 2 O 4 :Cr 3+ (mZGC) afterglow NIR-emitting nanocomposites that are made by a simple, one-s…