A Novel Polymorphism of the CYP4A11 Gene is Associated With Coronary Artery D…

CYP4A11 (cytochrome P450, family 4, subfamily A, polypeptide 11) converts arachidonic acid to 20- ydroxyeicosatetraenoic acid (20-HETE), which plays a crucial role in the modulation of cardiovascular homeostasis. The aim of the present study was to assess the association between the human CYP4A11 gene and coronary artery disease (CAD). Methods: A total of 361 patients with CAD and 315 controls …