The oxidation and reduction behavior of cefdinir (CEF) was studied by experimental methods and computational calculations at B3LYP/6-31þG (d)//AM1. Voltammetric studies were carried out based on two irreversible reduction peaks at approximately 0.5 and 1.2 V on a hanging mercury drop electrode (HMDE) and on one irreversible oxidation peak at approximately 1.0 V on a glassy carbon electrode …