DNase I hypersensitivity mapping, genomic footprinting, andtranscription fact…

Understanding gene regulatory networks in plants requires knowledge of cis-regulatory DNA, trans-actingfactors, and their dynamics across development and in response to stimuli. Active cis-regulatory elementsare hypersensitive to cleavage by the endonuclease DNase I. Motifs within DNase I hypersensitive sitesindicate potential trans-acting factor occupancy and, when combined with DNase I cleava…