Natural biochemical processes are controlled and regulated by different mechanisms at various levels of complexity involving numerous biochemical and physiological reactions.1 Artificial biocatalytic and particularly bioelectrocatalytic processes used in various bioelectronic devices, such as biosensors, biofuel cells, and bioactuators, are suffering from the lack of the biochemical control and…
ABSTRACT The modified electrode for electrocatalytic oxidation of NADH was developed using a pH-switchable redox interface. The operation of the modified electrode was controlled by logic operations performed by enzyme systems processing biochemical input signals. The electrocatalytic oxidation of NADH was activated upon appropriate combinations of the signals processed by the AND/OR logic op…