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Beyond Traditional Biosafety
Biosafety professionals have ever-expanding roles at their institutions. In this Beyond Traditional Biosafety column, we focus on topics that may fall outside the scope of the traditional biosafety role, but where the expertise of the biosafety professional may be called upon to provide a valuable contribution to his or her institution
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- Vol. 20, No. 2, 2015
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- Deskripsi Fisik
- Applied Biosafety Vol. 20, No. 2, 2015, 110-114
- Judul Seri
- Applied Biosafety
- No. Panggil
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Assessing the Biological Safety Profession’s Evaluation and Control of Risk…
Abstract: Because the origins of the biological safety profession are rooted in the control and prevention of laboratory-associated infections, the vocation focuses primarily on the safe handling of specimens within the laboratory. But in many cases, the Specimens and samples handled in the lab are originally collected in the field where a broader set of possible exposure considerations may be…
- Edisi
- Vol. 20, No. 1, 2015
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- Applied Biosafety Vol. 20, No. 1, 2015, 27-40
- Judul Seri
- Applied Biosafety
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Understanding the Challenges in the Design, Installation, and Commissioning o…
Abstract: Biocontainment doors are a key part of high-containment shells and an integral part of a complex system. Designing a facility for these doors, as well as their installation and commissioning, is a challenging task. This article reviews biosafety regulations and standards to decipher when and where biocontainment doors are required within a high-containment facility. It then illustrat…
- Edisi
- Vol. 20, No. 2, 2015
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- Applied Biosafety Vol. 20, No. 2, 2015, 80-88
- Judul Seri
- Applied Biosafety
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Removal of Botulinum Neurotoxin A Surrogate from Reusable Medical Device Surf…
Abstract: Botulinum neurotoxin A (BoNT/A) is on the national select agent registry and can be an extremely potent biotoxin if weaponized. It blocks neuromuscular transmission by decreasing acetylcholine release. This may be a serious problem if expensive reusable medical devices such as ventilators or anesthesia machines are accidentally or deliberately contaminated. Since transfer of BoNT/A f…
- Edisi
- Vol. 20, No. 2, 2015
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- Applied Biosafety Vol. 20, No. 2, 2015, 104-109
- Judul Seri
- Applied Biosafety
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Vaccinia Virus—Laboratory Tool with a Risk of Laboratory-acquired Infection
Abstract: The vaccinia virus vaccine was effectively used during the 19th and 20th centuries to eradicate smallpox. Over the last decade, vaccinia virus and derived recombinant vectors have been increasingly used in biomedical research, in preclinical animal studies, as well as in clinical trials. While laboratories engineer and test orthopoxvirus vaccine vectors against infectious diseases an…
- Edisi
- Vol. 20, No. 1, 2015
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- Applied Biosafety Vol. 20, No. 1, 2015, 6-11
- Judul Seri
- Applied Biosafety
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Legacy Biological Materials
Abstract: The recent report of improperly stored smallpox samples in freezers within laboratories from another agency on the campus of the National Institutes of Health and several other publicized issues involving highly pathogenic or regulated materials have prompted laboratories around the country to ask questions about what they might have in storage. This article describes a series of p…
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- Vol. 20, No. 2, 2015
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- Applied Biosafety Vol. 20, No. 2, 2015, 99-103
- Judul Seri
- Applied Biosafety
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Occupational Health and Personnel Suitability for Biological Research Programs
Abstract: This article provides an outline of the federal government’s occupational health and personnel suitability guidance to work with certain highly infectious and dangerous pathogens. It also includes the results of a survey conducted by Arizona State University regarding the individual requirements to work with these materials. Research shows that a limited number of tools are availab…
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- Vol. 20, No. 1, 2015
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- Applied Biosafety Vol. 20, No. 1, 2015, 41-54
- Judul Seri
- Applied Biosafety
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A Flexible Approach to Imaging in ABSL-3 Laboratories
Abstract: In-life imaging of animals challenged experimentally with infectious agents greatly enhances the quality of data gained from a pathogenesis or efficacy study. This additional information also presents an opportunity to address ethical issues by refining the studies and reducing the number of animals used. Both magnetic resonance (MR) and computed tomography (CT) imaging modalities ar…
- Edisi
- Vol. 20, No. 2, 2015
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- Applied Biosafety Vol. 20, No. 2, 2015, 89-99
- Judul Seri
- Applied Biosafety
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The European Enforcement Project on Genetically Modified Organisms
Abstract: Genetically modified organisms (GMOs) are regulated in the European Union (EU) through directives, which governments of Member States must implement, to provide assurance that any GMO work undertaken is done so safely. In this article the work of a European network of GMO inspectors founded in 1997, the European Enforcement Project (EEP) on Genetically Modified Organisms, is explaine…
- Edisi
- Vol. 20, No. 1, 2015
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- Applied Biosafety Vol. 20, No. 1, 2015, 55-58
- Judul Seri
- Applied Biosafety
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Characterizing Accidents, Exposures, and Laboratory-acquired Infections Repor…
Abstract: The goal of this project is to identify and characterize the types of incidents, accidents, exposures, and subsequent infections involving recombinant DNA materials that have occurred since the inception of biotechnology and oversight by NIH from June 1976 through December 31, 2010, a period spanning approximately 35 years of recombinant DNA research. A total of 197 records were iden…
- Edisi
- Vol. 20, No. 1, 2015
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- Applied Biosafety Vol. 20, No. 1, 2015, 12-26
- Judul Seri
- Applied Biosafety
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Biosafety Tips
Biosafety Tips brings you practical approaches to biosafety or “news you can use.” If you are looking for a useful and sensible solution to a biocontainment problem orperhaps a reference to help convince a skeptical researcher about the need for caution, this is the place to look. In this column I share some biosafety insights for managing a variety of workplace situations. I welcome feedb…
- Edisi
- Vol. 20, No. 1, 2015
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- Applied Biosafety Vol. 20, No. 1, 2015 , 59-61
- Judul Seri
- Applied Biosafety
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The NIH Office of Biotechnology Activities Site Visit Program: Observations A…
Abstract: Biocontainment doors are a key part of high-containment shells and an integral part of a complex system. Designing a facility for these doors, as well as their installation and commissioning, is a challenging task. This article reviews biosafety regulations and standards to decipher when and where biocontainment doors are required within a high-containment facility. It then illustra…
- Edisi
- Vol. 20, No. 2, 2015
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- Applied Biosafety Vol. 20, No. 2, 2015, 75-80
- Judul Seri
- Applied Biosafety
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Nontyphoidal Salmonella: An Occupational Hazard for Clinical Laboratory Workers
Abstract: Laboratory-acquired infections due to nontyphoidal Salmonella are rare. Yet, recent outbreaks in microbiology teaching laboratories show that these species are still an appreciable occupational hazard for laboratory employees. This article presents two cases of nontyphoidal Salmonella that occurred at the authors’ institution—an infected patient and a clinical laboratory worker w…
- Edisi
- Vol. 20, No. 2, 2015
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- Applied Biosafety Vol. 20, No. 2, 2015, 72-74
- Judul Seri
- Applied Biosafety
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Biosafety in the Field: An Account of a Kyrgyz Antiplague Expedition
Abstract: The Soviet Union had a unique system to control plague (causative agent, Yersinia pestis) and other “especially dangerous diseases.” This system continues to exist in many of the countries of the former Soviet Union, although with more limited funding. One of the key activities of the antiplague system is to look for the causative agent of plague in its natural reservoirs in the …
- Edisi
- Vol. 19, No. 2, 2014
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- Applied Biosafety Vol. 19, No. 2, 2014, 74-86
- Judul Seri
- Applied Biosafety
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Incident Reporting and Biosafety Training in a BSL-3 Select Agent Facility
Abstract: Incident reporting is an important component of any biosafety program. Effective analysis of incident report data can be used to evaluate compliance with standard operating procedures (SOPs) and the safety of different procedures and laboratorians, with the overall goal of preventing future incidents. This study analyzed incident reports from a BSL-3 select agent facility over a 3-y…
- Edisi
- Vol. 19, No. 4, 2014
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- Applied Biosafety Vol. 19, No. 4, 2014, 192-200
- Judul Seri
- Applied Biosafety
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Japan’s RIKEN BSI: Whole Facility Chlorine Dioxide Gas Decontamination Appr…
Abstract: This article discusses one of Japan’s newest research facilities—the RIKEN Brain Science Institute. The Brain Science Institute (BSI) conducts research that integrates multiple disciplines including medicine, biology, psychology, physics, computer science, and technology, and utilizes several different rodent models in a clean barrier facility. This article discusses the specific…
- Edisi
- Vol. 19, No. 4, 2014
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- Applied Biosafety Vol. 19, No. 4, 2014, 201-210
- Judul Seri
- Applied Biosafety
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Characterization of Recombinant Vaccinia Viruses by MLPA Technology
Abstract: Recombinant vaccinia viruses are popular tools for the delivery of heterologous genes for vaccination purposes. Vaccinia viruses are generally classified as risk group 2 biological agents (in accordance to directive 2000/54/EC), with the attenuated strain Modified vaccinia virus Ankara (MVA) being classified into risk group 1. For the analytical surveillance of genetic engineering op…
- Edisi
- Vol. 19, No. 3, 2014
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- Applied Biosafety Vol. 19, No. 3, 2014, 132-140
- Judul Seri
- Applied Biosafety
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New Entity CDC Select Agent Registration Process—A Practical Guide to Lesso…
Abstract: Entities planning to conduct work in the United States with biological select agents and toxins (BSAT) must be registered with either the Centers for Disease Control and Prevention (CDC) or the Animal and Plant Health Inspection Service (APHIS) of the United States Department of Agriculture (USDA). Information pertaining to registration is described in a Guidance Document for Complet…
- Edisi
- Vol. 19, No. 2, 2014
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- Applied Biosafety Vol. 19, No. 2, 2014, 56-67
- Judul Seri
- Applied Biosafety
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Ebola 2014: Clarifying the Confusion—A Public Health and Laboratory Contain…
Abstract: The 2014 West African Ebola outbreak has spawned a chain of preparedness planning in the United States (U.S.). Although clinical and public health laboratories are hard at work preparing for the presentation of highly suspect patients, a number of issues have been identified that need to be addressed. Guidelines have been developed and distributed; procedures need to be revised and t…
- Edisi
- Vol. 19, No. 3, 2014
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- Applied Biosafety Vol. 19, No. 3, 2014, 118-123
- Judul Seri
- Applied Biosafety
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Systems Approach to Biosafety and Risk Assessment of Engineered Nanomaterials
Abstract: The need for nanomaterials biosafety and risk assessment is an offshoot of the widespread use of nanoscale particle (NP)-derived materials in over 300 nanotechnology-based products already in commerce, including over 70 healthcarerelatedproducts (WWICS, 2006). Rapid advances in material sciences research and the advent of new and highly sophisticated nanofabrication technologies have…
- Edisi
- Vol. 19, No. 1, 2014
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- Applied Biosafety Vol. 19, No. 1, 2014, 11-19
- Judul Seri
- Applied Biosafety
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Quantification of Microbial Aerosol Generation During Standard Laboratory Pro…
Abstract: Laboratory containment systems are designed to removen potentially infectious aerosolized particles from the worker’s environment. However, little evidence on the quantities of aerosol generated during common microbiological practices exists. This study’s objective was to measure aerosol and splash contamination during the microbiology techniques of serial dilution and pipettin…
- Edisi
- Vol. 19, No. 3, 2014
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- Applied Biosafety Vol. 19, No. 3, 2014, 124-131
- Judul Seri
- Applied Biosafety
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The Importance of Fit-Testing Particulate Filtering Facepiece Respirators!
Abstract: Filtering facepiece respirators should protect people in healthcare settings and in research and diagnostic laboratories from infection from biological agents or from other hazardous particles. To ensure sufficient personal protection, a properly fitting respirator is imperative. However, data about the usefulness of testing the proper fit of such respirators conflict. Some data fro…
- Edisi
- Vol. 19, No. 4, 2014
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- Applied Biosafety Vol. 19, No. 4, 2014,184-192
- Judul Seri
- Applied Biosafety
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Characterization of Respirable Aerosols Generated During Routine Laboratory P…
Abstract: Biosafety Level 2 (BSL-2) and Biosafety Level 3 (BSL-3) facility lab personnel routinely perform procedures that are capable of producing respirable aerosols. While these procedures are considered safe when performed in the closed environment of a biosafety cabinet (BSC), there are, nevertheless, limited data regarding the nature of the aerosols these procedures produce. This lack …
- Edisi
- Vol. 19, No. 1, 2014
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- Applied Biosafety Vol. 19, No. 1, 2014, 19-27
- Judul Seri
- Applied Biosafety
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Implementation of an Occupational Health and Medical Surveillance Program at …
Abstract: Historically in the United States, occupational health and medical surveillance programs for biodefense laboratories that work with Biological Select Agents and Toxins (BSAT) or other infectious organisms are sponsored by the federal government (DoD, HHS, USDA, etc.) or state universities (Jahrling et al., 2009; Kortepeter et al., 2008; Risi et al., 2010). These programs are operated…
- Edisi
- Vol. 19, No. 1, 2014
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- Applied Biosafety Vol. 19, No. 1, 2014, 4-10
- Judul Seri
- Applied Biosafety
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Molecular Biosafety
Conclusions: We do not yet know whether the “Seek and Kill” E. coli system will demonstrate effective and safe pathogen cell killing in in vivo situations, for other pathogens, or as a broad spectrum antimicrobial, but the well-designed Hwang et al. study provides enough positive results to make their approach a promising avenue to pursue.
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- Vol. 19, No. 1, 2014
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- Applied Biosafety Vol. 19, No. 1, 2014, 38-40
- Judul Seri
- Applied Biosafety
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A Survey of Biosafety and Biosecurity Practices in the United States Army Med…
Abstract: USAMRU-K Department of Emerging Infectious Diseases (DEID) is a program consisting of eight facilities (laboratories) that are centrally administered. It has instituted safety regulations in the past 5 years under specific safety standard operating procedures (SOPs) with a goal to minimize work-related risks, injuries, or illnesses to laboratory and clinical workers by ensuring that…
- Edisi
- Vol. 19, No. 1, 2014
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- Applied Biosafety Vol. 19, No. 1, 2014, 28-34
- Judul Seri
- Applied Biosafety
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The Effects of Patient Movement on Particles Dispersed by Coughing in an Indo…
Abstract: This study investigates the influence of a moving patient on the transport characteristics of coughing particles by dynamic meshing and the Lagrangian particle tracking method. Through simulation, particle movement during the initial coughing, patient movement, and stationary flow phases was examined. Two different particle sizes (5 μm and 10 μm) were used and yielded small differ…
- Edisi
- Vol. 19, No. 4, 2014
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- Applied Biosafety Vol. 19, No. 4, 2014, 172-183
- Judul Seri
- Applied Biosafety
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Quantitative Measurement of Legionella pneumophila Counts in Routinely Mainta…
Abstract: Cooling towers are associated with transmission of the bacterium Legionella, the agent of Legionnaires’ Disease and Pontiac Fever. This study analyzed the numbers of Legionella pneumophila collected from 1,336 commercial and industrial cooling towers over a 4-year period. These cooling towers were routinely treated with biocides to reduce the growth of Legionella. Comparisons of L…
- Edisi
- Vol. 19, No. 2, 2014
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- Applied Biosafety Vol. 19, No. 2, 2014, 64-73
- Judul Seri
- Applied Biosafety
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The Value of Biosafety Professionals
Abstract: The life science industry continues to grow in leaps and bounds. Novel biological discoveries occur every day. Although in recent years the dollars spent for federally-funded biological research has decreased, the regulatory requirements under which this work must be conducted have expanded, and along with it, the responsibilities of the biosafety professional. In general, the role o…
- Edisi
- Vol. 19, No. 2, 2014
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- Applied Biosafety Vol. 19, No. 2, 2014, 87-97
- Judul Seri
- Applied Biosafety
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The Feasibility of Using a Rapid Adenosine Triphosphate Bioluminescence Assay…
Abstract: The underlying causes of many reported laboratory associated infections (LAIs) are often not objectively identified and are generally attributed to poor laboratory technique or surface contamination in the laboratory. While training and practice can enhance laboratory technique, an objective evaluation of laboratory surface cleanliness is typically not performed. However, this is no…
- Edisi
- Vol. 19, No. 3, 2014
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- Applied Biosafety Vol. 19, No. 3, 201, 141-148
- Judul Seri
- Applied Biosafety
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Failure Mode Testing During Verification Identifies Mechanical Failure in an …
Abstract: Annual verification of an Animal Biosafety Level 3 (ABSL- 3) facility’s design and operational procedures is recommended by the Biosafety in Microbiological and Biomedical Laboratories (5th edition) (BMBL) (U.S. Department of Health and Human Services, 2009) and conducted by Iowa State University (ISU) Biosafety personnel by repeating initial verification testing. Annual verificat…
- Edisi
- Vol. 18, No. 2, 2013
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- Applied Biosafety Vol. 18, No. 2, 2013, 81-7
- Judul Seri
- Applied Biosafety
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The Formalization of a Biological Safety Program at the National Institute of…
Abstract: In recent years, research efforts and measurement capabilities in biological science have significantly increased at the National Institute of Standards and Technology (NIST). Biological experiments are often performed by NIST physicists, chemists, and engineers who are not traditionally trained in biological safety protocols. A biosafety working group comprised of research scientis…
- Edisi
- Vol. 18, No. 4, 2013
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- Applied Biosafety Vol. 18, No. 4, 2013, 187-190
- Judul Seri
- Applied Biosafety
- No. Panggil
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Inactivation of Bacillus anthracis Spores on All-weather Paper
Abstract: This study evaluated the inactivation of Bacillus anthracis Ames strain on all-weather paper using 1% and 6% sodium hypochlorite (NaOCl). A suspension of approximately 1 x 108 colony forming units (CFU) of B. anthracis was dried on papercoupons and exposed to either 1% or 6% NaOCl (with or without the addition of surfactant) by wiping with a bleach-soaked towel or by spraying with a…
- Edisi
- Vol. 18, No. 3, 2013
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- Applied Biosafety Vol. 18, No. 3, 2013, 132-137
- Judul Seri
- Applied Biosafety
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Integrating Safety in Science—How to Get Scientists’ Buy-in
Abstract: Universities have Occupational Health and Safety Offices where safety professionals ensure compliance with regulations through the establishment of policies, procedures, and instructions. This traditional approach is being replaced by a more proactive system-based, comprehensive, business management approach known as a Safety Management System (SMS). The Duke-NUS (National University…
- Edisi
- Vol. 18, No. 4, 2013
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- Applied Biosafety Vol. 18, No. 4, 2013, 172-177
- Judul Seri
- Applied Biosafety
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Biosafety, Biosecurity, and Bioethics Governance in Synthetic Biology: The �…
Abstract: While recognizing the importance of synthetic biology as an emerging field within science and technology, as well as its potential benefits toward economic growth, public health, energy, and the environment, this article argues that the biorisks involved from a biosafety, biosecurity, and bioethics perspective need to be addressed. To do so, a comprehensive approach combining the two…
- Edisi
- Vol. 18, No. 4, 2013
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- Applied Biosafety Vol. 18, No. 4, 2013, 178-186
- Judul Seri
- Applied Biosafety
- No. Panggil
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Efficacy of Polarized Fibreglass Filters Irradiated by Ultraviolet Light in C…
Abstract: In this study, spores of Bacillus subtilis were used as a surrogate for spores of Bacillus anthracis. The mock-up air purification system consisted of one or two V-shaped banks of electrostatically polarized fibreglass filters that were installed within a rectangular wooden duct. Ultraviolet (UV) lights that swept across the surface of the filters were installed in front and back of …
- Edisi
- Vol. 18, No. 2, 2013
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- Applied Biosafety Vol. 18, No. 2, 2013, 73-80
- Judul Seri
- Applied Biosafety
- No. Panggil
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Showering BSL-4 Suits to Remove Biological Contamination
Abstract: Positive pressure suits are widely used at BSL-4 to protect operators from contact with microbiological agents. As there is the potential for the outside of the suits to become contaminated during use, they must be decontaminated prior to final exit from the high-containment laboratory. Chemical showers are used to remove biological material from suits, and the shower effluent is co…
- Edisi
- Vol. 18, No. 4, 2013
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- Deskripsi Fisik
- Applied Biosafety Vol. 18, No. 4, 2013, 162-171
- Judul Seri
- Applied Biosafety
- No. Panggil
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Green Genes
The Green Genes column focuses on biotechnology research and use of genetically modified plants for crop improvement, medical and veterinary biologics, alternative fuels, and environmental remediation. Genetically modified plants show promise for benefits to global health and the environment. At the same time, biotechnology research and products must be safe for the environment (flora and wildl…
- Edisi
- Vol. 18, No. 1, 2013
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- Deskripsi Fisik
- Applied Biosafety Vol. 18, No. 1, 2013, 37-39
- Judul Seri
- Applied Biosafety
- No. Panggil
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Mold Remediation of a Research Facility in a Hospital
Abstract: A hospital’s life science research facility experienced flooding due to a pipe bursting two floors above. In addition to water damage throughout the facility, mold spores were introduced and distributed throughout. Prior to repairs being made, a full facility decontamination took place to eliminate any mold or mold spores throughout the facility. Chlorine dioxide gas (CD) was chos…
- Edisi
- Vol. 18, No. 4, 2013
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- Deskripsi Fisik
- Applied Biosafety Vol. 18, No. 4, 2013, 191-196
- Judul Seri
- Applied Biosafety
- No. Panggil
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Removal of a Natural Toxin Surrogate from Water, Material Surfaces, and Reus…
Abstract: Water and reusable medical device surfaces can be contaminated by natural toxins such as ricin either accidentally or intentionally. This report focuses on the removal of peanut lectin (PL), a ricin surrogate, from water and reusable medical devices and materials. An ELISA assay was used to determine if commercially available water filters could remove peanut lectin from water, and i…
- Edisi
- Vol. 18, No. 1, 2013
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- Deskripsi Fisik
- Applied Biosafet Vol. 18, No. 1, 2013, 23-29
- Judul Seri
- Applied Biosafet
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Hand Washing Quality among Biosafety Level 2 Research Laboratory Workers
Abstract: Soap and water hand washing (HW) is recommended as the standard microbiological practice for removing transient microbes from laboratory workers’ hands. The effectiveness of HW in preventing pathogen transmission depends largely on the technique used by the individual, but little is known about laboratory workers’ compliance with recommended HW protocols. This study evaluated th…
- Edisi
- Vol. 18, No. 3, 2013
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- Deskripsi Fisik
- Applied Biosafety Vol. 18, No. 3, 2013, 116-121
- Judul Seri
- Applied Biosafety
- No. Panggil
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Salary Indicators for Biosafety Professionals
Abstract: The biosafety and biosecurity profession has seen significant growth over the past several decades. The implementation of biosafety-related regulations and associated guidance documents has helped fuel the need for technically qualified professionals in the field. The objective of this article is to evaluate the factors that contribute to the salaries of biosafety professionals. In o…
- Edisi
- Vol. 18, No. 3, 2013
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- Applied Biosafety Vol. 18, No. 3, 2013,
- Judul Seri
- Applied Biosafety
- No. Panggil
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Laboratory Decontamination of HHS-listed and HHS/USDA Overlap Select Agents a…
Abstract: This review describes the susceptibilities of all currently HHS-listed and HHS/USDA Overlap select agents and toxins to 8 chemical and 2 physical decontaminants: alcohols, aldehydes, bleach/hypochlorite, iodine, peroxides, phenolics, quaternary ammonium compounds, strong base, dry heat, and steam autoclaving. Inactivation protocols from the literature are presented to facilitate de…
- Edisi
- Vol. 18, No. 2, 2013
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- Applied Biosafety Vol. 18, No. 2, 2013, 59-72
- Judul Seri
- Applied Biosafety
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A Practical Guide to Implementing a BSL-2+ Biosafety Program in a Research La…
Abstract: Biosafety Level Two Plus (BSL-2+) is a term frequently used to describe laboratories where work with microorganisms is conducted in a BSL-2 laboratory with biosafety practices and procedures typically found at BSL-3. The risk assessment process may determine that safety practices over and above those required at BSL-2 are needed for a research project, yet a more complex BSL-3 labora…
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- Vol. 18, No. 1, 2013
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- Applied Biosafety Vol. 18, No. 1, 2013, 30-36
- Judul Seri
- Applied Biosafety
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The Endurance Testing Process: A Methodology to Verify the Functionality of B…
Abstract: Biocontainment facilities planning to possess or work with biological select agents and toxins (BSAT) require registration with the National Select Agent Registry. The registration process includes submission of documentation for review to either the Centers for Disease Control and Prevention (CDC) Select Agent Program or the U.S. Department of Agriculture (USDA) Animal and Plant He…
- Edisi
- Vol. 18, No. 1, 2013
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- Deskripsi Fisik
- Applied Biosafety Vol. 18, No. 1, 2013, 18-23
- Judul Seri
- Applied Biosafety
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Biosafety Risk Assessment and Management of Laboratory-derived Influenza A (H…
Abstract: Highly pathogenic avian influenza (HPAI) A (H5N1) viruses occasionally infect humans, but currently do not transmit efficiently among them. However, the risk for human pandemic influenza is a major concern should these viruses acquire the capacity for human-to-human transmission and retain their current virulence. Recently, two research teams have succeeded in modifying HPAI A (H5N…
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- Vol. 18, No. 1, 2013
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- Applied Biosafety Vol. 18, No. 1, 2013, 6-17
- Judul Seri
- Applied Biosafety
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First Report: Application of MALDI-TOF MS within an External Quality Assuranc…
Abstract: In this article the authors describe the application of Matrix Assisted Laser Desorption/Ionization Time-of-Flight (MALDITOF) Intact Cell Mass Spectrometry (ICMS) within a proficiency test organized by a European Union (EU)-funded project on the topic of Establishment of Quality Assurances for Detection of Highly Pathogenic Bacteria of Potential Bioterrorism Risk (EQADeBa). In total …
- Edisi
- Vol. 17, No. 2, 2012
- ISBN/ISSN
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- Deskripsi Fisik
- Applied Biosafety Vol. 17, No. 2, 2012, 59-63
- Judul Seri
- Applied Biosafety
- No. Panggil
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Study on the Testing Method to Determine the Performance of Personal Respirat…
Abstract: Respiratory illnesses are increasingly recognized as a growing concern for healthcare workers (HCWs) and patients. The 2003 hospital-based outbreak of Severe Acute Respiratory Syndrome (SARS) has once again highlighted the vulnerability of HCWs to aerosol-transmitted viral infections. Personal respiratory protective equipment was one of the key means for the HCWs to avoid nosocomial…
- Edisi
- Vol. 17, No. 1, 2012
- ISBN/ISSN
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- Deskripsi Fisik
- Applied Biosafety Vol. 17, No. 1, 2012, 26-30
- Judul Seri
- Applied Biosafety
- No. Panggil
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Testing of Emergency Showers Made Painless
Conclusion: The device provides a good and simple solution for emergency shower testing. Laboratory staff performs the test on a monthly rotation basis. This ensures that the laboratory staff takes ownership of the emergency equipment and knows the location of the showers. Table 1 provides a measure of key parameters before and after implementing the use of this device
- Edisi
- Vol. 17, No. 1, 2012
- ISBN/ISSN
- -
- Deskripsi Fisik
- Applied Biosafety Vol. 17, No. 1, 2012, 23-25
- Judul Seri
- Applied Biosafety
- No. Panggil
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Analysis of the Class III Biological Safety Cabinet Integrity Test
Abstract: The Class III Biological Safety Cabinet (BSC) provides maximum personnel protection when it is adequately field certified and properly used. One of the major criteria for this protection is proper performance of the Class III BSC integrity (tracer gas) test as described in the National Institutes of Health Laboratory Safety Monograph (NCI, 1979). This article deals with the origins, …
- Edisi
- Vol. 17, No. 3, 2012
- ISBN/ISSN
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- Deskripsi Fisik
- Applied Biosafety Vol. 17, No. 3, 2012, 128-131
- Judul Seri
- Applied Biosafety
- No. Panggil
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