1. Using scripting languages such as R to perform population genetic analyses can improve the reproducibility of research, but usingRcan be challenging for many researchers due to its steep learning curve. 2. POPGENREPORT is a new R package that simplifies performing population genetics analyses in R, through the use of a new report-generating function. The function POPGENREPORT allows users…
Decreasing the soaring energy cost is imperative in large data centers. Meanwhile, limited computational resources need to be fairly allocated among different organizations. Latency is another major concern for resource management. Nevertheless, energy cost, resource allocation fairness, and latency are important but often contradicting metrics on scheduling data center workloads. Moreover, wit…
This paper proposes a novel scheme of nonuniform discretizetion-based control vector parameterization (ndCVP, for short) for dynamic optimization problems (DOPs) of industrial processes. In our ndCVP scheme, the time span is partitioned into a multitude of uneven intervals, and incremental time parameters are encoded, along with the control parameters, into the individual to be optimized. Our c…
Abstract—Essential proteins are vital for an organism’s viability under a variety of conditions. There are many experimental and computational methods developed to identify essential proteins. Computational prediction of essential proteins based on the global protein-protein interaction (PPI) network is severely restricted because of the insufficiency of the PPI data, but fortunately the ge…
This paper proposes a novel concept for simultaneous cell shape and motion analysis in fast microchannel flows by implementing a multiobject feature extraction algorithm on a framestraddling high-speed vision platform. The system can synchronize two camera inputs with the same view with only a tiny time delay on the sub-microsecond timescale. Real-time video processing is performed in hardware…
Objectives: We conduct a revaluation of the Thornhill and Fincher research project on parasites using finelyresolved geographic data on parasite prevalence, individual-level sociocultural data, and multilevel Bayesian modeling. In contrast to the evolutionary psychological mechanisms linking parasites to human behavior and cultural characteristics proposed by Thornhill and Fincher, we offer a…
Arable weeds are one of the most endangered species groups in Europe. Modern agriculture and intensive land-use management are the main causes of their dramatic decline. However, besides the changes in land use, climate change may further challenge the adaptability of arable weeds. Therefore, we investigated the response pattern of arable weeds to different water potential and temperature regim…
Linear drain current degradation of a field-gate p-channel lateral extended drain MOS (FG-pLEDMOS) transistor for different ac hot-carrier stress conditions has been experimentally investigated in this paper. It is noted that hot-carrier degradation strongly depends on the time of the rising and falling edges of the gate signal pulse. Faster rising and falling edges of the gate pulse will indu…
This paper considers a customer order scheduling problem with product type splitting property in the unrelated parallel machine environment. Product type splitting property refers to the case where each customer order consists of several product types and the workload of all associated product types can be arbitrarily split among machines. The objective is to minimize the total completion time…
Human activity is among the critical information for a context-aware energy saving system since knowing what activities are undertaken is important for judging if energy is well spent. Most of the prior works on energy saving do not make the best of context-awareness especially in a multiuser environment to assist the energy saving system. In addition, they often ignore whether appliances are …
This paper deals with the design and the experimental validation in scale-lab test benches of an energy management algorithm based on feedback control techniques for a flywheel energy storage device. The aim of the flywheel is to smooth the net power injected to the grid by a wind turbine or by a wind power plant. In particular, the objective is to compensate the power disturbances produced by …
A generic state-vector transition (SVT) model is suggested, including a flexible synchronous composition involving both shared variables and events. This model is analyzed, focusing on properties that are important for supervisor synthesis. A synthesis procedure is then developed for the SVT model, where supervisor guards are generated that guarantee a controllable, nonblocking and maximally pe…
This paper presents the modeling approach for a quasi-2-D tubular anode-supported solid-oxide fuel cell (SOFC) for real-time control implementation. The proposed system considers a multidomain electrochemical, fluidic, and thermal dynamic modeling and it is experimentally validated against a SOFC real world implementation. Implicit iterative algebraic equations have been introduced and impleme…
A popular clustering algorithm for biological networks which was proposed by Hartuv and Shamir [5] identifies nonoverlapping highly connected components. We extend the approach taken by this algorithm by introducing the combinatorial optimization problem HIGHLY CONNECTED DELETION, which asks for removing as few edges as possible from a graph such that the resulting graph consists of highly conn…
The rapid development of gene ontology (GO) and huge amount of biomedical data annotated by GO terms necessitate computation of semantic similarity of GO terms and, in turn, measurement of functional similarity of genes based on their annotations. In this paper we propose a novel and efficient method to measure the semantic similarity of GO terms. The proposed method addresses the limitations i…
Mobile cloud computing (MCC) improves the computational capabilities of resource-constrained mobile devices. On the other hand, the mobile users demand a certain level of quality-of-service (QoS) provisioning while they use services from the cloud, even if the interfacing gateway changes due to the mobility of the users. In this paper, we identify, formulate, and address the problem of QoS-guar…
We address the problem of providing users with the ability to assess the integrity of join results produced by external computational providers and computed over externally stored databases. Our approach relies on different mutually supporting techniques offering strong integrity protection guarantees at a limited cost. The application of the approach is completely transparent to the computatio…
Ananalysis for net power characterization of a proton exchange membrane fuel cell (PEMFC) system is developed with Ballard 1.2-kW Nexa power module. A net power control (NPC)strategy based on the linear matrix inequality (LMI) approach is proposed to achieve optimal oxygen excess ratio (OER). The H∞ suboptimal control problem is solved by LMI and the simulations are carried out under differe…
Aluminum-doped zinc oxide (AZO) thin films have been used in low cost transparent conductive oxide (TCO) applications. For flexible electronics, the devices are subjected to cyclic bending during manufacturing and usage, which may lead to both electrical and optical degradation of TCO thin films. This paper was designed to investigate the effect of the strained growth and normal growth methods …
Synchronizing sequences have been proposed in the late 1960s to solve testing problems on systems modeled by finitestate machines. Such sequences lead a system, seen as a black box, from an unknown current state to a known final one. This paper presents a first investigation of the computation of synchronizing sequences for systems modeled by synchronized Petri nets. In the first part of the p…
Cepaea’ vindobonensis has been shown to be closely related to Caucasotachea in recent molecular studies. The phylogenetic relationships within this clade and especially the phylogenetic position of ‘Cepaea’ vindobonensis were, however, not well resolved. Our phylogenetic analyses on the basis of an increased number of molecular genetic loci from the mitochondrial and nuclear genomes unamb…
Establishing phylogenetic relationships of miniature fishes is challenging in taxa with developmental truncation. Within the Characiformes, developmental truncation appears to be relatively rare, with the Neotropical genus Priocharax being an example. Priocharax includes three miniature species among the smallest of the order and has been hypothesized to belong to the Heterocharacinae. The p…
In numerous cellular applications, cells are transported to specific positions or extracted from complex cell solutions. Therefore, an efficient cell transportation path planner for these applications is important for avoiding collisions with other cells or obstacles. In this paper, a path planning approach to transporting cells using a robot-aided optical manipulation system is presented. Opt…
A novel parameters estimation strategy of interior permanent magnet synchronous machine (IPMSM) for accurate torque control is proposed and investigated in this paper. The difference of q-axis inductance and d-axis inductance is estimated by a PI regulator using the deviation between actual output power and reference power. The estimated difference of dq inductance can be used to achieve maxim…
Abstract—Pathway deregulation has been identified as a key driver of carcinogenesis, with proteins in signaling pathways serving as primary targets for drug development. Deregulation can be driven by a number of molecular events, including gene mutation, epigenetic changes in gene promoters, verexpression, and gene amplifications or deletions. We demonstrate a novel approach that identifies p…
This paper presents a novel real-time powerdevice temperature estimation method that monitors the power MOSFET’s junction temperature shift arising from thermal aging effects and incorporates the updated electrothermal models of power modules into digital controllers. Currently, the real-time estimator is emerging as an important tool for active control of device junction temperature as well…
Hidden Markov Models (HMMs) are powerful tools for multiple sequence alignment (MSA), which is known to be an NPcomplete and important problem in bioinformatics. Learning HMMs is a difficult task, and many meta-heuristic methods, including particle swarm optimization (PSO), have been used for that. In this paper, a new variant of PSO, called the random drift particle swarm optimization (RDPSO) …
Correlation factors between different ESD pulse types for different back-end-of-line (BEOL) metal-line topologies have been studied to support system-level on-chip ESD design. The component level (HMM, HBM, and TLP on a wafer) and system-level (IEC gun contact on package) ESD stresses were correlated followed by extraction of correlation factors between the IEC/HMM and TLP, as well as the HBM a…
Variability in resistive switching memory (RRAM) devices is studied by applying an AC measurement setup capable of efficiently collecting read current data in low and high resistance states (LRS and HRS, respectively) in each consecutive pulse SET/RESET cycle. It is found that HRS and LRS read current values follow the lognormal and normal distributions, respectively. Endurance test demonstrat…
The subject of this paper is high-speed induction motor (IM) with drag-cup rotor with low inertia, designed for use in high-speed automotive applications such as kinetic energy recovery system (KERS). The aim of this paper is to present the optimization procedure of the air-gap length and the rotor thickness of this kind of motor in order to achieve the highest efficiency in the speed and torqu…
In this paper, we assess the performance of a ring oscillator and a DRAM cell when they are implemented with different technologies (planar CMOS, FinFETs, and III–V MOSFETs), and subjected to different reliability scenarios (variability and soft errors). FinFET-based circuits show the highest robustness against variability and soft error environments. Index Terms—DRAM, integrated circuit r…
This paper proposes a robust adaptive voltage control of three-phase voltage source inverter for a distributed generation system in a standalone operation. First, the state-space model of the load-side inverter, which considers the uncertainties of system parameters, is established. The proposed adaptive voltage control technique combines an adaption control term and a state feedback control te…
The effect of conductor spacing and applied voltage on the insulation performance of printed circuit board (PCB) has been investigated under temperature–humidity–bias (THB) conditions in this paper. Based on the electrochemical migration failure mechanism, this paper proposes an accelerated statistical model, which includes a life–stress relationship model and a life distribution model. …
A liquid-cooled eddy current retarder (ECR) with a dual salient poles design is proposed in this paper. Finite element models were developed to perform transient magnetic analysis and steady-state conjugate heat transfer analysis. The braking torque, eddy current field and thermal field of the retarder were each predicted. The retarder was subjected to two sets of tests on a test bench, to obta…
This paper presents a new computational technique for the identification of HIV haplotypes. HIV tends to generate many potentially drug-resistant mutants within the HIV-infected patient and being able to identify these different mutants is important for efficient drug administration. With the view of identifying the mutants, we aim at analyzing short deep sequencing data called reads. From a s…
Abstract—MicroRNA (miRNA) plays an important role as a regulator in biological processes. Identification of (pre-) miRNAs helps in understanding regulatory processes. Machine learning methods have been designed for pre-miRNA identification. However, most of them cannot provide reliable predictive performances on independent testing data sets. We assumed this is because the training sets, espe…
This paper proposes an integrated event-based binaural silicon cochlea system aimed at efficient spatial audition and auditory scene analysis. The cochlea chip has a matched pair of digitally-calibrated 64-stage cascaded analog second-order filter banks with 512 pulse-frequency modulated (PFM) address-event representation (AER) outputs. The quality factors (Qs) of channels are individually adj…
Modern manufacturing facilities waste many energy savings opportunities (ESO) due to the lack of integration between the facility and the production system. To explore the energy savings opportunities, this paper combines the two largest energy consumers in a manufacturing plant: the production line and the heating, ventilation, and air conditioning (HVAC) system. The concept of the energy oppo…
New requirements for the validation of simulation models based on measurements in many grid codes show that existing generic approaches for generator and converter models of doubly fed generator systems (DFG) may not be accurate enough. The authors show that by applying a detailed analysis of the generator equations and the converter control design, a reduction of the model complexity is possi…
This work presents a novel feature extraction approach called nonuniform scale-frequency map for environmental sound classification in home automation. For each audio frame, important atoms from the Gabor dictionary are selected by using the Matching Pursuit algorithm. After the system disregards phase and position information, the scale and frequency of the atoms are extracted to construct a s…
In this paper, a 3-D finite-element (FE) model was established based on real test samples. Coupled electrothermal and thermal–mechanical FE analyses were conducted to analyze the mechanical behavior of bonding wire under cyclic power loading. The current crowding phenomenon may be improved by increasing the wire number. The junction temperature can be decreased by decreasing the joule heat f…
The nymphal stages of Palaeozoic insects differ significantly in morphology from those of their modern counterparts. Morphological details for some previously reported species have recently been called into question. Palaeozoic insect nymphs are important, however – their study could provide key insights into the evolution of wings, and complete metamorphosis. Here we review past work on t…
In this paper, a noncontact proximity vital sign sensor, using a phase locked loop (PLL) incorporated with voltage controlled oscillator (VCO) built-in planar type circular resonator, is proposed to enhance sensitivity in severe environments. The planar type circular resonator acts as a series feedback element of the VCO as well as a near-field receiving antenna. The frequency deviation of the …
The major histocompatibility complex (MHC), a cell-surface protein mediating immune recognition, plays important roles in the immune response system of all higher vertebrates. MHC molecules are highly polymorphic and they are grouped into serotypes according to the specificity of the response. It is a common belief that a protein sequence determines its three dimensional structure and function.…
Automated protein function prediction is one of the grand challenges in computational biology. Multi-label learning is widely used to predict functions of proteins. Most of multi-label learning methods make prediction for unlabeled proteins under the assumption that the labeled proteins are completely annotated, i.e., without any missing functions. However, in practice, we may have a subset of …
Public cloud platforms might start with homogeneous hardware; nevertheless, because of inevitable hardware upgrades, or adding more capacity, the initial homogeneous platform will gradually evolve into heterogeneous as time passes by. The consequent performance heterogeneity is of concern to cloud users. In this paper, we evaluate performance variations from hardware heterogeneity and schedulin…
Array comparative genomic hybridization (aCGH) is a newly introduced method for the detection of copy number abnormalities associated with human diseases with special focus on cancer. Specific patterns in DNA copy number variations (CNVs) can be associated with certain disease types and can facilitate prognosis and progress monitoring of the disease. Machine learning techniques have been used t…
Siderastrea siderea is one of the most abundant corals at high latitude shallow sites along the Florida Reef Tract (25°–27°N). This species is able to tolerate wide seawater temperature fluctuations and sedimentation stress, but its reproductive status at high latitudes and under marginal environmental conditions is poorly understood. The objectives of this study were to evaluate the reprod…
To meet the electrical performance requirements, copper traces with ultralow-k (ULK) interlayer dielectric (ILD) materials are used in today’s semiconductor devices. The dielectric constant (k) of these materials is often reduced through the introduction of pores or inclusions, and thus, the ULK ILD materials have low fracture strength. During flip-chip assembly, thermally induced stresses oc…
This paper investigates the problem of robust model predictive control (RMPC) with saturations and packet dropouts. In this model, polytopic uncertainties are adopted to describe the inconsistency arising from the discretization process of sampling, while the occurrence probabilities of packet dropouts are time-varying and saturations are taken into account to describe input and output signals.…